Exposure to Lead during Critical Windows of Embryonic Development: Differential Immunotoxic Outcome Based on Stage of Exposure and Gender

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Exposure to lead during critical windows of embryonic development: differential immunotoxic outcome based on stage of exposure and gender.

Previous rat studies with lead (Pb) have shown that exposure throughout the full gestational period results in persistent immunotoxicity detectable in both juvenile and adult offspring. Gender differences are also evident. However, little is known about the persistent immunotoxic effects of Pb when administered during specific stages of embryonic development. Adult Sprague-Dawley female rats we...

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ژورنال

عنوان ژورنال: Toxicological Sciences

سال: 2001

ISSN: 1096-6080,1096-0929

DOI: 10.1093/toxsci/64.1.57